| Acronym | Definition |
|---|
| SED | Special Education |
| SED | Stream Editor |
| SED | State Education Department |
| SED | Sedalia (Amtrak station code; Sedalia, MO) |
| SED | Shipper's Export Declaration |
| SED | Systems Engineering and Development (US DHS) |
| SED | Social and Emotional Development (education) |
| SED | Spondyloepiphyseal Dysplasia (bone growth disorder) |
| SED | Serious Emotional Disturbance |
| SED | South Eastern Division (UK) |
| SED | School of English and Drama (UK) |
| SED | Sound Editor Deluxe (software) |
| SED | Sociedad Española del Dolor (Spanish: Spanish Society of Pain) |
| SED | Surface-Conduction Electron-Emitter Display |
| SED | Senior Executive Director (various organizations) |
| SED | Sozialistische Einheitspartei Deutschlands (Socialist Union Party of East Germany) |
| SED | Sony Energy Devices (Japan) |
| SED | Structured Electronic Document (data transmission) |
| SED | Surface Conduction Electron Emitter Display |
| SED | Self Extracting Directive |
| SED | Strategic Economic Dialogue |
| SED | Sciences and Exploration Directorate (US NASA) |
| SED | Severely Emotionally Disturbed |
| SED | Socio-Economic Development |
| SED | Spectral Energy Distribution |
| SED | Self-Encrypting Drive |
| SED | Survey of Earned Doctorates |
| SED | Sedating |
| SED | Small Electronic Device |
| SED | Seeing-Eye Dog |
| SED | Small Enterprise Development |
| SED | Safety Engineered Device (healthcare) |
| SED | School Education Director (Australia) |
| SED | Software Engineering Directorate |
| SED | Survey of English Dialects |
| SED | Supported Education |
| SED | Scottish Enterprise Dunbartonshire (UK) |
| SED | Systems Engineering Division |
| SED | Sustainable Energy Development |
| SED | Schweizerischer Erdbebendienst (Swiss Seismological Service) |
| SED | Standard Error of the Difference (statistics) |
| SED | Signals External Data (US DoD) |
| SED | Self Employment Development (various organizations) |
| SED | Selective Eating Disorder (psychology) |
| SED | Software Error Density (ratio) |
| SED | Special Enforcement Detail |
| SED | Strain Energy Density |
| SED | Science Education Department |
| SED | Smoke-Emitting Diode |
| SED | Site Equipment Demonstration (exhibition) |
| SED | School of Environmental Design |
| SED | Software Engineering Design |
| SED | Solar Energy Division (American Society of Mechanical Engineers) |
| SED | Squared Euclidean Distance |
| SED | Science, Environment and Development |
| SED | Skill Enhancement Division |
| SED | Statistical Engineering Division |
| SED | Spanish Education Development |
| SED | Secondary Electron Detector |
| SED | Shore Establishments Division (US Navy) |
| SED | Severe Emotional Disability |
| SED | Service d'Enseignement à Distance (French: Services for Distance Learning) |
| SED | Sweet Eagle Dreams |
| SED | Single-Event Disturb |
| SED | Skin Erythema Dose |
| SED | Single Error Detection |
| SED | Satellite Eligibility Determination (site) |
| SED | Special Events Director |
| SED | Suberythemal Dose |
| SED | Sub-clinical Eating Disorder |
| SED | Severely Employment Disadvantaged |
| SED | Sensor Evolutionary Development (aeronautics) |
| SED | Spacecraft Engineering Department |
| SED | Société Etudes Développements (French engineering company) |
| SED | Senior Executive Development |
| SED | Sub-Entire Domain |
| SED | Service d'Expérimentation et de Développement (French: Experimentation and Development Office; National Institute for Research in Computer Science and Control) |
| SED | Special Electrical Devices |
| SED | Special Engineers Detachment (Manhattan Project) |
| SED | Sub-Epithelial Domain (biology) |
| SED | Short Edge Distance |
| SED | Sales, Engineering and Development |
| SED | Strip Endpoint Diffraction |
| SED | System Evolution Description |
| SED | Sedom, Israel - Domestic Airfield (airport code) |
| SED | State Emergency Duty (Missouri) |
| SED | Service des Etablissements de Détention (French: Office of Detention Facilities; Switzerland) |
| SED | Space Exploration Day |
| SED | Soulever et Déplacer (French: Lift and Move; moving company) |
| SED | Standard Erytemdos |