“oleandomycin”的英文意思_释义_用法

单词

oleandomycin

释义

oleandomycin Pharm.|ˌəʊliːændəʊˈmaɪsɪn|
[f. oleand-rose, a sugar of which a residue is present in the oleandomycin molecule (f. oleandrine + -ose²) + -o + -mycin.]
(The phosphate of) a macrolide, C₃₅H₆₁NO₁₂, produced by a strain of the bacterium Streptomyces antibioticus, which is active against a wide range of Gram-positive bacteria and has been used in treating staphylococcal enteritis and skin infections.
1956B. A. Sobin et al. U.S. Pat. 2,757,123 31 July, This invention relates to a new and useful antibiotic called oleandomycin.1967[see erythromycin].1968[see macrolide].1974D. Perlman in W. O. Foye Princ. Med. Chem. xxxi. 742/1 Oleandomycin, a macrolide bacterial antibiotic closely related to erythromycin, has been losing value as a therapeutic agent for infections caused by gram-positive bacteria because of high incidence of side effects.

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