| 单词 |
podocyte |
| 释义 |
podocyte, n. Anat.|ˈpɒdəʊsaɪt|
[f. podo- + -cyte.]
Each of the epithelial cells whose irregular pinnate processes envelop the capillaries of the glomerular capsules of the kidney, interlocking with those of other such cells to form the outermost layer of the barrier through which substances are filtered out of the blood.
1954B. V. Hall in Proc. 5th Ann. Conf. Nephrotic Syndrome i. 9 This figure shows the characteristic irregularities of the nuclear membrane of the so-called epithelial cells, which we have termed podocytes. 1960Jrnl. Urol. LXXXIII. 791/1 The podocytes (foot cells) sit upon the glomerular basement membranes with thousands of little ‘pedicels’ (Hall) or foot processes. 1978Nephron XXII. 439/2 It has been suggested that aminonucleoside induces proteinuria by a toxic action on podocytes. 1988Acta Anat. CXXXIII. 303/2 In this model of polycystosis, glomerular cysts develop, whose presumptive parietal layer is exclusively formed by podocytes.
Hence podoˈcytic a., pertaining to, consisting of, or designating a podocyte or podocytes.
1955B. V. Hall in Proc. 6th Ann. Conf. Nephrotic Syndrome i. 2 These large processes were called trabeculae; incompletely pictured here in section on the left of the micrograph and to the right of the podocytic nucleus. 1957Amer. Heart Jrnl. LIV. 5 The endothelial ultrafiltration slit-pore may be confined to the folded borders of the endothelial cells, so that its total area is probably very much less than that of the podocytic slit-pore. 1979Nature 29 Feb. 655/2 They form junctional complexes with the parietal epithelium of Bowman's capsule on one side and visceral podocytic epithelium on the other. 1988Laboratory Investigation LIX. 677/2 The podocytic microfilament system may actively modify the width of the slit pores and thus may be able to regulate the solute efflux across the glomerular wall. |
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